Classes > 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile
Page last updated: 2024-08-05 12:42:30
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile
A nitrile that is 1,3-dihydro-2-benzofuran-5-carbonitrile in which one of the hydrogens at position 1 is replaced by a p-fluorophenyl group, while the other is replaced by a 3-(dimethylamino)propyl group.
ChEBI ID: 77397
Members (2)
| Member | Definition | Role |
|---|
| (R)-citalopram | A 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile that has R-configuration at the chiral centre. It is the inactive enantiomer of citalopram. | (R)-citalopram |
| escitalopram | A 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile that has S-configuration at the chiral centre. It is the active enantiomer of citalopram. | escitalopram |
Research
Studies (223)
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (1.35) | 29.6817 |
| 2010's | 19 (8.52) | 24.3611 |
| 2020's | 201 (90.13) | 2.80 |
Study Types
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|
| Trials | 55 (23.81%) | 5.53% |
| Reviews | 14 (6.06%) | 6.00% |
| Case Studies | 6 (2.60%) | 4.05% |
| Observational | 1 (0.43%) | 0.25% |
| Other | 155 (67.10%) | 84.16% |